Tender Details

Country: Netherlands
Summary: Custom-Made Mrna (Gmp)
NLT Ref No: 117533682
Deadline: 26 May 2025
Financier: Self Financed
Purchaser Ownership: Government
Tender Value: EUR 1
Notice Type: Tender
Document Ref. No.: 236986-2025
Purchaser's Detail:
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Description:
The Department of Medical BioSciences from Radboudumc has been awarded a KWF grant for the PROTECT-lynch study. The main goal of the PROTECT-lynch study is a new treatment option for LS patients significantly improving the quality of life of LS patients and most likely the prognosis (occurrence of Lynch-related cancer(s). Standard care for healthy LS patients currently consists of undergoing intensive surveillance programs that do not guarantee timely detection of one or more Lynch-related cancers at a treatable stage. The PROTECT-lynch study may change this with its preventive dendritic cell therapy. To prepare the intended dendritic cell (DC) product for the PROTECT-lynch study, mRNA coding for carcino-embryonic antigen (CEA) is required in GMP quality. As the Medical BioSciences department, we have extensive experience in the preparation of DC products in collaboration with the Pharmacy department, in which comparable mRNA was used as raw material for the DC product. The mRNA will form a complex with protamine, which will be added as stimulant to the DC product to fully mature the DCs. For this extensive project the Medical BioSciences department is looking for a reliable supplier of custom-made mRNA in GMP quality in the requested quantities. Depending on the stability of the mRNA, execution of stability studies of the mRNA according to ICH guidelines and strict timelines may be needed. This manufacturer must hold a GMP manufacturing certificate and have their production ...
Documents:

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Custom-Made Mrna (Gmp) - Netherlands Tender

The RADBOUD UNIVERSITAIR MEDISCH CENTRUM/RADBOUDUMC, a Government sector organization in Netherlands, has announced a new tender for Custom-Made Mrna (Gmp). This tender is published on NetherlandsTenders under NLT Ref No: 117533682 and is categorized as a Tender. Interested and eligible suppliers are invited to participate by reviewing the tender documents and submitting their bids before the deadline on 2025-05-26.

The estimated tender value is EUR 1, and full details, including technical specifications and submission requirements, are provided in the official tender documents. Ensure all submissions meet the criteria outlined to be considered for evaluation.